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Recent Posts

Bio-identical Hormones

Bioidentical Hormone Replacement Therapy in California

Just What are Bio-identical Hormones?

Bioidentical hormones are manufactured in the lab to have the same molecular structure as the hormones made by your own body. By contrast, synthetic hormones are intentionally different. Drug companies can’t patent a bioidentical structure, so they invent synthetic hormones that are patentable (Premarin, Prempro, and Provera being the most widely used examples). Though bioidentical hormones have been around for years, most practitioners are unfamiliar with them. There are several branded versions now available for use in the kind of hormone replacement therapy typical of synthetic hormones. This is often a one-size-fits-all dosage regime. Dr. Kohani has had the greatest success with an individualized approach. She begins with laboratory...

Hormone and Emotion Therapy

Hormones and Emotions, How Are They Connected?

Estradiol and Serotonin At optimal levels, estradiol (E2) supports serotonin in several ways: E2 increases tryptophan hydroxylase, the rate-limiting step in serotonin synthesis E2 receptor (E2β) simulation upregulates the expression of serotonin receptors (5-HT2A) E2 acts as a serotonin reuptake inhibitor E2 inhibits monoamine oxidase activity, thus preventing the breakdown of serotonin Consequently, if estradiol levels decrease, serotonin activity may decrease as well. Low estradiol levels may result in symptoms associated with low serotonin, e.g. low mood, sleep difficulties, hot flashes, uncontrolled appetite, and headaches. Supporting serotonin may counter the effects of decreased estradiol. [vc_empty_space height="25px"][eltd_section_title enable_separator="yes" alignment="left" title_h_element="h2" title="Progesterone and GABA" title_color="#000000"][vc_empty_space height="15px"][vc_column_text]Progesterone's metabolite allopregnanolone acts at the GABA...

Hormones and Immune System

Hormones, Emotions and Immune System, They are All Interconnected.

The human body consists of multiple systems that communicate to maintain homeostasis and health. The coordinated interconnectedness of the nervous, endocrine, and immune systems is often overlooked when considering patient care. Nevertheless, our health is hinged on the existence of neurotransmitters, hormones, and cytokines, which are essential chemical signals that mediate the communication between the nervous, endocrine, and immune systems, respectively. Collectively, these systems constitute the Neuro-Endo-Immune (NEI) Supersystem. Taking a closer look at the role of endocrinology in the NEI supersystem, there are several important hormone-neurotransmitter interactions and three axes at which much hormone-neurotransmitter-cytokine interaction occurs; including the hypothalamic-pituitary-adrenal (HPA) axis, the hypothalamic-pituitary-thyroid (HPT) axis, and the...